This model from Bionet is an optimal bioreactor/fermentor for microbial and cell culture production. It includes autoclavable bench-scale bioreactor, designed to meet the challenging and widely diverse R&D requirements. This model is perfect for biopharmaceutical, food, agricultural, and other biotechnological applications.

This model is available with a glass vessel in the following volumes:

  • 0.5 L, single or double-wall vessel,
  • 1 L, single or double-wall vessel,
  • 3 L, single or double-wall vessel,
  • 5 L, single or double-wall vessel, and
  • 10 L, single or double-wall vessel.

You can also double-up with the possibility to perform parallel bioprocessing with the TWIN version of the equipment.

If you are interested in consulting our experts on getting an F1 bioreactor for your lab, contact us at This email address is being protected from spambots. You need JavaScript enabled to view it. or via the form at the bottom of the page.

Though it’s serially produced and standardised to combine the highest technological solutions for the common market demands, it is well thought for its expansion and customisation towards a range of special requirements. This is made possible thanks to:

Advanced gas module

This module allows the automatic mixing of up to four gases (O2, N2, CO2, air) and their inlet through overlay and sparger. This means that we can regulate pH (acidification) of the broth with acid or carbon dioxide (CO2) and nitrogen (N2) as an actuator in the dissolved oxygen (DO) cascade.

The continuous process module

This module allows the extraction and addition of fresh media for the continuous process. It can also be used for extraction, the addition of media, and separation of biomass in the perfusion process. The pump in the module has reversible direction and operating speed from 4 to 200 rpm.

The variable speed pump

This pump is perfect for nutrient addition in the fed-batch process based on the growth of the cells and growth profiles. The pump can also be used in the cascade control mode of dissolved oxygen (DO). The pump has reversible direction and variable speeds; 4, 30, or 100 rpm.

Add extras or keep it default

The bioreactor unit can be paired with a broad range of spare electronics/sensors.

Because of the software flexibility, we can integrate a variety of in-situ process analytical technologies:

  • optical density sensors,
  • gas analyzers, and
  • glucose sensors.

These sensors and their measurements can be integrated into advanced control strategies. With the integration of a wide range of analytical technologies, the software also enables visualisation and use of measurements in advanced bioprocess control loops.

Spare parts and accessories

We are offering a wide range of add-ons, which allow the flexibility of the operation and easier handling of the bioreactor. From height-adjustable dip tubes, easy to clean additions nozzle, robust and interchangeable vessel supports, and more.


F1 offers the possibility to upgrade the equipment to GMP standards at the hardware (i.e. mechanically), software, and documentation levels.

Controlled by ROSITA

The F1 is designed to share the same space and the same automation software with other F1 units, increasing your lab capacity. ROSITA is Bionet’s automation software for laboratory use. The software allows for a sophisticated and tight automatic control over the processes and provides the user with ways to visualise, analyse, and manage the data.


If you are interested in getting an F1 bioreactor for your lab, contact us at This email address is being protected from spambots. You need JavaScript enabled to view it. or fill out the form below.

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